Microsoft's MAI-DxO diagnostic system published in Science
Microsoft
Microsoft published MAI-DxO in Science on October 22, 2026, a diagnostic orchestrator that scored 83% on 304 complex NEJM cases versus 22% for physicians without reference resources and 36% with them, and 80% versus 47% on MIMIC-IV-ED emergency cases. A cost-optimized configuration reached 81% accuracy at under half the cost of comparison systems, and a clinical study with Beth Israel Deaconess is planned.
Why it matters
A peer-reviewed result of this size on sequential diagnosis is the strongest clinical evidence yet for orchestrated multi-model medical reasoning.
Importance: 4/5
peer-reviewed flagship result in Science with strong benchmark margins
Sources
official
Building Medical Superintelligence
official
MAI-DxO sequential diagnosis study